preparation and evaluation of zinc sulfate sustained release tablets using lipophilic and hydrophilic matrix

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formulation and evaluation of sustained release matrix tablets of glipizide

the purpose of this study was to develop a new monolithic matrix tablet to completely deliver glipizide in a zero order manner over a sustained period. two approaches were examined using drug in a formulation that contain polymer like hydroxylpropyl methyl-cellulose k 100 (hpmck) and eudragit l 100. the granules were prepared by wet granulation method and thereby formulated as f-1, f-2. f-3 and...

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preparation and in vitro evaluation of sustained-release matrix tablets of flutamide using synthetic and naturally occurring polymers

frequent dosing of the potent anti-androgen, flutamide, is necessary to reach a therapeutic level for the treatment of prostatic carcinoma. sustained delivery of the drug could reduce the adverse effects such as gastrointestinal disorders and improve patient compliance. in the present study sustained-release matrix tablets of flutamide were prepared by direct compression method using different ...

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Journal title:
research in pharmaceutical sciences

جلد ۷، شماره ۵، صفحات ۰-۰

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